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A chromosomal position effect on gene targeting in human cells
We describe gene targeting experiments involving a human cell line (RAN10) containing, in addition to its endogenous alleles, two ectopic alleles of the interferon-inducible gene 6–16. The frequency of gene targeting at one of the ectopic 6–16 alleles (H3.7) was 34-fold greater than the combined fre...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137162/ https://ncbi.nlm.nih.gov/pubmed/12433992 |
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