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A chromosomal position effect on gene targeting in human cells

We describe gene targeting experiments involving a human cell line (RAN10) containing, in addition to its endogenous alleles, two ectopic alleles of the interferon-inducible gene 6–16. The frequency of gene targeting at one of the ectopic 6–16 alleles (H3.7) was 34-fold greater than the combined fre...

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Hlavní autoři: Yáñez, Rafael J., Porter, Andrew C. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC137162/
https://ncbi.nlm.nih.gov/pubmed/12433992
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