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The effect of target site transcription on gene targeting in human cells in vitro.

We evaluate the effect of target site transcription on gene targeting in cultured human fibrosarcoma cells. A number of cell lines that harbored a plasmid recombination substrate within their chromosomal DNA were created. Gene targeting frequency was then measured at these different loci in the pres...

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Détails bibliographiques
Auteurs principaux: Thyagarajan, B, Johnson, B L, Campbell, C
Format: Artigo
Langue:Inglês
Publié: 1995
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC307105/
https://ncbi.nlm.nih.gov/pubmed/7651841
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