Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms

Recently, recurrent mutations of spliceosomal genes were frequently identified in myeloid malignancies, as well as other types of cancers. One of these spliceosomal genes, U2AF1, was affected by canonical somatic mutations in aggressive type of myeloid malignancies. We hypothesized that U2AF1 mutati...

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Autores principales: Przychodzen, Bartlomiej, Jerez, Andres, Guinta, Kathryn, Sekeres, Mikkael A., Padgett, Richard, Maciejewski, Jaroslaw P., Makishima, Hideki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2013
Materias:
Myeloid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739042/
https://ncbi.nlm.nih.gov/pubmed/23775717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-01-480970
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