Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms

Recently, recurrent mutations of spliceosomal genes were frequently identified in myeloid malignancies, as well as other types of cancers. One of these spliceosomal genes, U2AF1, was affected by canonical somatic mutations in aggressive type of myeloid malignancies. We hypothesized that U2AF1 mutati...

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Autori principali: Przychodzen, Bartlomiej, Jerez, Andres, Guinta, Kathryn, Sekeres, Mikkael A., Padgett, Richard, Maciejewski, Jaroslaw P., Makishima, Hideki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2013
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739042/
https://ncbi.nlm.nih.gov/pubmed/23775717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-01-480970
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