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Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning

Hedgehog (HH) signaling is essential for vertebrate and invertebrate embryogenesis. In Drosophila, feedback upregulation of the HH receptor Patched (PTC; PTCH in vertebrates), is required to restrict HH signaling during development. By contrast, PTCH1 upregulation is dispensable for early HH-depende...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Holtz, Alexander M., Peterson, Kevin A., Nishi, Yuichi, Morin, Steves, Song, Jane Y., Charron, Frédéric, McMahon, Andrew P., Allen, Benjamin L.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Company of Biologists 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737722/
https://ncbi.nlm.nih.gov/pubmed/23900540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.095083
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