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Bithiazole Correctors Rescue CFTR Mutants by Two Different Mechanisms

[Image: see text] Better correctors are needed to repair cystic fibrosis transmembrane conductance regulator (CFTR) processing mutants that cause cystic fibrosis. Determining where the correctors bind to CFTR would aid in the development of new correctors. A recent study reported that the second nuc...

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Autors principals: Loo, Tip W., Bartlett, M. Claire, Clarke, David M.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2013
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737597/
https://ncbi.nlm.nih.gov/pubmed/23865422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4008758
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