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Bithiazole Correctors Rescue CFTR Mutants by Two Different Mechanisms

[Image: see text] Better correctors are needed to repair cystic fibrosis transmembrane conductance regulator (CFTR) processing mutants that cause cystic fibrosis. Determining where the correctors bind to CFTR would aid in the development of new correctors. A recent study reported that the second nuc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Loo, Tip W., Bartlett, M. Claire, Clarke, David M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2013
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737597/
https://ncbi.nlm.nih.gov/pubmed/23865422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4008758
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