Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy

The nuclear receptor Rev-erb-α modulates hepatic lipid and glucose metabolism, adipogenesis and the inflammatory response in macrophages. We show here that Rev-erb-α is highly expressed in oxidative skeletal muscle and plays a role in mitochondrial biogenesis and oxidative function, in gain- and los...

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Detalhes bibliográficos
Main Authors: Woldt, Estelle, Sebti, Yasmine, Solt, Laura A., Duhem, Christian, Lancel, Steve, Eeckhoute, Jérôme, Hesselink, Matthijs K.C., Paquet, Charlotte, Delhaye, Stéphane, Shin, Youseung, Kamenecka, Theodore M., Schaart, Gert, Lefebvre, Philippe, Nevière, Rémi, Burris, Thomas P., Schrauwen, Patrick, Staels, Bart, Duez, Hélène
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737409/
https://ncbi.nlm.nih.gov/pubmed/23852339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3213
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