Three-dimensional culture sensitizes epithelial ovarian cancer cells to EZH2 methyltransferase inhibition

Inhibitors of EZH2 methyltransferase activity have been demonstrated to selectively suppress the growth of diffused large B cell lymphoma (DLBCL) cells with gain-of-function mutations in EZH2, while exhibiting very limited effects on the growth of DLBCL cells with wild-type EZH2. Given that EZH2 is...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Amatangelo, Michael D., Garipov, Azat, Li, Hua, Conejo-Garcia, Jose R., Speicher, David W., Zhang, Rugang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2013
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737313/
https://ncbi.nlm.nih.gov/pubmed/23759589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25163
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