Fancd2 and p21 function independently in maintaining the size of hematopoietic stem and progenitor cell pool in mice

Fanconi anemia patients suffer from progressive bone marrow failure. An overactive p53 response to DNA damage contributes to the progressive elimination of Fanconi anemia hematopoietic stem and progenitor cells (HSPC), and hence presents a potential target for therapeutic intervention. To investigat...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Qing-Shuo, Watanabe-Smith, Kevin, Schubert, Kathryn, Major, Angela, Sheehan, Andrea M., Marquez-Loza, Laura, Hanlon Newell, Amy E., Benedetti, Eric, Joseph, Eric., Olson, Susan, Grompe, Markus
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737285/
https://ncbi.nlm.nih.gov/pubmed/23721813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2013.04.010
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