Fancd2(−/−) mice have hematopoietic defects that can be partially corrected by resveratrol

Progressive bone marrow failure is a major cause of morbidity and mortality in human Fanconi Anemia patients. In an effort to develop a Fanconi Anemia murine model to study bone marrow failure, we found that Fancd2(−/−) mice have readily measurable hematopoietic defects. Fancd2 deficiency was associ...

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Autors principals: Zhang, Qing-Shuo, Marquez-Loza, Laura, Eaton, Laura, Duncan, Andrew W., Goldman, Devorah C., Anur, Praveen, Watanabe-Smith, Kevin, Rathbun, R. Keaney, Fleming, William H., Bagby, Grover C., Grompe, Markus
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Hematopoiesis and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012535/
https://ncbi.nlm.nih.gov/pubmed/20826722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-278226
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