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Antidepressants, metoprolol and the risk of bradycardia

Case reports and pharmacologic theory suggest that some antidepressants can interfere with the hepatic metabolism of metoprolol by cytochrome P450 2D6 (CYP2D6), potentially increasing the risk of bradycardia. The objective of this study was to characterize the clinical consequences of this potential...

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Bibliografske podrobnosti
Main Authors: Kurdyak, Paul A., Manno, Michael, Gomes, Tara, Mamdani, Muhammad M., Juurlink, David N.
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736934/
https://ncbi.nlm.nih.gov/pubmed/23983956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045125311433580
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