The risk of hypotension following co-prescription of macrolide antibiotics and calcium-channel blockers

BACKGROUND: The macrolide antibiotics clarithromycin and erythromycin may potentiate calcium-channel blockers by inhibiting cytochrome P450 isoenzyme 3A4. However, this potential drug interaction is widely underappreciated and its clinical consequences have not been well characterized. We explored t...

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Bibliografiske detaljer
Main Authors: Wright, Alissa J., Gomes, Tara, Mamdani, Muhammad M., Horn, John R., Juurlink, David N.
Format: Artigo
Sprog:Inglês
Udgivet: Canadian Medical Association 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042440/
https://ncbi.nlm.nih.gov/pubmed/21242274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.100702
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