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Antidepressants, metoprolol and the risk of bradycardia

Case reports and pharmacologic theory suggest that some antidepressants can interfere with the hepatic metabolism of metoprolol by cytochrome P450 2D6 (CYP2D6), potentially increasing the risk of bradycardia. The objective of this study was to characterize the clinical consequences of this potential...

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Autores principales: Kurdyak, Paul A., Manno, Michael, Gomes, Tara, Mamdani, Muhammad M., Juurlink, David N.
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736934/
https://ncbi.nlm.nih.gov/pubmed/23983956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045125311433580
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