טוען...
Venous malformation-causative TIE2 mutations mediate an AKT-dependent decrease in PDGFB
Mutations in the endothelial cell (EC) tyrosine kinase receptor TIE2 cause inherited and sporadic forms of venous malformation. The recurrent somatic mutation L914F and common germline mutation R849W differ in terms of phosphorylation level, as well as sub-cellular localization and trafficking of th...
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| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736867/ https://ncbi.nlm.nih.gov/pubmed/23633549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt198 |
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