Načítá se...

Venous malformation-causative TIE2 mutations mediate an AKT-dependent decrease in PDGFB

Mutations in the endothelial cell (EC) tyrosine kinase receptor TIE2 cause inherited and sporadic forms of venous malformation. The recurrent somatic mutation L914F and common germline mutation R849W differ in terms of phosphorylation level, as well as sub-cellular localization and trafficking of th...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Uebelhoer, Melanie, Nätynki, Marjut, Kangas, Jaakko, Mendola, Antonella, Nguyen, Ha-Long, Soblet, Julie, Godfraind, Catherine, Boon, Laurence M., Eklund, Lauri, Limaye, Nisha, Vikkula, Miikka
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736867/
https://ncbi.nlm.nih.gov/pubmed/23633549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt198
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!