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High Throughput Screen for Pharmacoperones of the Vasopressin Type 2 Receptor
Pharmacoperone drugs correct the folding of misfolded protein mutants and restore function (i.e. “rescue”) by correcting the routing of (otherwise) misrouted mutants. Assays for pharmacoperones have not been applied to screen large libraries previously. Currently most pharmacoperones possess intrins...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735853/ https://ncbi.nlm.nih.gov/pubmed/23640875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113483559 |
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