Cardiac Surgical Delivery of the Sarcoplasmic Reticulum Calcium ATPase Rescues Myocytes in Ischemic Heart Failure

BACKGROUND: The sarcoplasmic reticulum calcium ATPase (SERCA2a) is an important molecular regulator of contractile dysfunction in heart failure. Gene transfer of SERCA2a mediated by molecular cardiac surgery with recirculating delivery (MCARD) is a novel and clinically translatable strategy. METHODS...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fargnoli, Anthony S., Katz, Michael G., Yarnall, Charles, Isidro, Alice, Petrov, Michael, Steuerwald, Nury, Ghosh, Sriparna, Richardville, Kyle C., Hillesheim, Richard, Williams, Richard D., Kohlbrenner, Erik, Stedman, Hansell H., Hajjar, Roger J., Bridges, Charles R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735816/
https://ncbi.nlm.nih.gov/pubmed/23773730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2013.04.021
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