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Regulation of cholesterol and bile acid homeostasis by the CYP7A1/SREBP2/miR-33a axis
Bile acid synthesis not only produces physiological detergents required for intestinal nutrient absorption, but also plays a critical role in regulating hepatic and whole body metabolic homeostasis. We recently reported that over-expression of cholesterol 7α-hydroxylase (CYP7A1) in the liver resulte...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735649/ https://ncbi.nlm.nih.gov/pubmed/23536474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26427 |
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