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Regulation of cholesterol and bile acid homeostasis by the CYP7A1/SREBP2/miR-33a axis

Bile acid synthesis not only produces physiological detergents required for intestinal nutrient absorption, but also plays a critical role in regulating hepatic and whole body metabolic homeostasis. We recently reported that over-expression of cholesterol 7α-hydroxylase (CYP7A1) in the liver resulte...

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Detalhes bibliográficos
Main Authors: Li, Tiangang, Francl, Jessica M., Boehme, Shannon, Chiang, John Y. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735649/
https://ncbi.nlm.nih.gov/pubmed/23536474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26427
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