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MiR-33 Contributes to the Regulation of Cholesterol Homeostasis
Cholesterol metabolism is tightly regulated at the cellular level. Here we show that miR-33, an intronic microRNA (miRNA) located within the gene encoding sterol-regulatory element–binding factor–2 (SREBF-2), a transcriptional regulator of cholesterol synthesis, modulates the expression of genes inv...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3114628/ https://ncbi.nlm.nih.gov/pubmed/20466885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1189862 |
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