MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

Cholesterol metabolism is tightly regulated at the cellular level. Here we show that miR-33, an intronic microRNA (miRNA) located within the gene encoding sterol-regulatory element–binding factor–2 (SREBF-2), a transcriptional regulator of cholesterol synthesis, modulates the expression of genes inv...

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Autors principals: Rayner, Katey J., Suárez, Yajaira, Dávalos, Alberto, Parathath, Saj, Fitzgerald, Michael L., Tamehiro, Norimasa, Fisher, Edward A., Moore, Kathryn J., Fernández-Hernando, Carlos
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114628/
https://ncbi.nlm.nih.gov/pubmed/20466885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1189862
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