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MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis
Proper coordination of cholesterol biosynthesis and trafficking is essential to human health. The sterol regulatory element binding proteins (SREBPs) are key transcription regulators of genes involved in cholesterol biosynthesis/uptake. We show here that microRNAs (miR-33a/b) embedded within introns...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840500/ https://ncbi.nlm.nih.gov/pubmed/20466882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1189123 |
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