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Vitamin C controls the cystic fibrosis transmembrane conductance regulator chloride channel

Vitamin C (l-ascorbate) is present in the respiratory lining fluid of human lungs, and local deficits occur during oxidative stress. Here we report a unique function of vitamin C on the cystic fibrosis (CF) transmembrane conductance regulator (CFTR), a cAMP-dependent Cl channel that regulates epithe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fischer, Horst, Schwarzer, Christian, Illek, Beate
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC373524/
https://ncbi.nlm.nih.gov/pubmed/14993613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308393100
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