Vitamin C controls the cystic fibrosis transmembrane conductance regulator chloride channel

Vitamin C (l-ascorbate) is present in the respiratory lining fluid of human lungs, and local deficits occur during oxidative stress. Here we report a unique function of vitamin C on the cystic fibrosis (CF) transmembrane conductance regulator (CFTR), a cAMP-dependent Cl channel that regulates epithe...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Fischer, Horst, Schwarzer, Christian, Illek, Beate
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 2004
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14993613/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308393100
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