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Improved synthesis of N1-substituted orotic acid derivatives
An improved method for the synthesis of N1-substituted orotic acid derivatives is reported. The method involves sequential incorporation of nitrogen atoms to the pyrimidine structure from simple starting materials and thus allows the synthesis of N1-substituted orotic acid derivatives with single (1...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3735222/ https://ncbi.nlm.nih.gov/pubmed/23935222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.05.136 |
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