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Synthesis of Novel Lipophilic N-Substituted Norcantharimide Derivatives and Evaluation of Their Anticancer Activities

This research attempted to study the effect of lipophilicity on the anticancer activity of N-substituted norcantharimide derivatives. Twenty-three compounds were synthesized and their cytotoxicities against five human cancer cell lines studied. The lipophilicity of each derivative was altered by its...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Wu, Jin-Yi, Kuo, Cheng-Deng, Chu, Chien-Yu, Chen, Min-Shin, Lin, Jia-Hua, Chen, Yu-Jen, Liao, Hui-Fen
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271113/
https://ncbi.nlm.nih.gov/pubmed/24865603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19066911
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