Silencing of CXCR4 Blocks Breast Cancer Metastasis

RNA interference technology, silencing targeted genes in mammalian cells, has become a powerful tool for studying gene function. For the first time in cancer research, we show that direct injection of a pool of naked small interfering RNA (siRNA) duplexes can prevent tumorigenesis in an animal model...

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Main Authors: Liang, Zhongxing, Yoon, Younghyoun, Votaw, John, Goodman, Mark M., Williams, Larry, Shim, Hyunsuk
Format: Artigo
Jezik:Inglês
Izdano: 2005
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734941/
https://ncbi.nlm.nih.gov/pubmed/15705897
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