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CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway

CXC chemokine receptor 4 (CXCR4) has been shown to play a critical role in chemotaxis and homing, which are key steps in cancer metastasis. There is also increasing evidence that links this receptor to angiogenesis; however, its molecular basis remains elusive. Vascular endothelial growth factor (VE...

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Detalhes bibliográficos
Main Authors: Liang, Zhongxing, Brooks, Joann, Willard, Margaret, Liang, Ke, Yoon, Younghyoun, Kang, Seunghee, Shim, Hyunsuk
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986788/
https://ncbi.nlm.nih.gov/pubmed/17559806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.05.182
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