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HDAC inhibitors induce tumor-cell-selective pro-apoptotic transcriptional responses
The identification of recurrent somatic mutations in genes encoding epigenetic enzymes has provided a strong rationale for the development of compounds that target the epigenome for the treatment of cancer. This notion is supported by biochemical studies demonstrating aberrant recruitment of epigene...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3734831/ https://ncbi.nlm.nih.gov/pubmed/23449455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.9 |
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