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The anticancer effects of HDAC inhibitors require the immune system

Histone deacetylase inhibitors (HDACis) are known to exert immunomodulatory effects. We have recently demonstrated that the therapeutic efficacy of HDACis against aggressive B-cell lymphoma and colon carcinoma relies on a functional immune system, in particular on the production of interferon γ (IFN...

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Sonraí Bibleagrafaíochta
Main Authors: West, Alison C, Smyth, Mark J, Johnstone, Ricky W
Formáid: Artigo
Teanga:Inglês
Foilsithe: Landes Bioscience 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962507/
https://ncbi.nlm.nih.gov/pubmed/24701376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27414
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