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PKC signaling prevents irradiation-induced apoptosis of primary human fibroblasts

Primary cells respond to irradiation by activation of the DNA damage response and cell cycle arrest, which eventually leads to senescence or apoptosis. It is not clear in detail which signaling pathways or networks regulate the induction of either apoptosis or senescence. Primary human fibroblasts a...

詳細記述

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書誌詳細
主要な著者: Bluwstein, A, Kumar, N, Léger, K, Traenkle, J, Oostrum, J van, Rehrauer, H, Baudis, M, Hottiger, M O
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734826/
https://ncbi.nlm.nih.gov/pubmed/23412390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.15
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