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Human VRK2 modulates apoptosis by interaction with Bcl-xL and regulation of BAX gene expression
VRK2 is a novel Ser-Thr kinase whose VRK2A isoform is located in the endoplasmic reticulum and mitochondrial membranes. We have studied the potential role that VRK2A has in the regulation of mitochondrial-mediated apoptosis. VRK2A can regulate the intrinsic apoptotic pathway in two different ways. T...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3734818/ https://ncbi.nlm.nih.gov/pubmed/23449449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.40 |
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