Cargando...

Human VRK2 modulates apoptosis by interaction with Bcl-xL and regulation of BAX gene expression

VRK2 is a novel Ser-Thr kinase whose VRK2A isoform is located in the endoplasmic reticulum and mitochondrial membranes. We have studied the potential role that VRK2A has in the regulation of mitochondrial-mediated apoptosis. VRK2A can regulate the intrinsic apoptotic pathway in two different ways. T...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Monsalve, D M, Merced, T, Fernández, I F, Blanco, S, Vázquez-Cedeira, M, Lazo, P A
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734818/
https://ncbi.nlm.nih.gov/pubmed/23449449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.40
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!