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Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment
This study, using mouse embryonic fibroblast (MEF) cells derived from ROCK1(−/−) and ROCK2(−/−) mice, is designed to dissect roles for ROCK1 and ROCK2 in regulating actin cytoskeleton reorganization induced by doxorubicin, a chemotherapeutic drug. ROCK1(−/−) MEFs exhibited improved actin cytoskeleto...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3734810/ https://ncbi.nlm.nih.gov/pubmed/23392171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.10 |
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