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ROCK1 Deficiency Enhances Protective Effects of Antioxidants against Apoptosis and Cell Detachment

We have recently reported that the homologous Rho kinases, ROCK1 and ROCK2, play different roles in regulating stress-induced stress fiber disassembly and cell detachment, and the ROCK1 deficiency in mouse embryonic fibroblasts (MEF) has remarkable anti-apoptotic, anti-detachment and pro-survival ef...

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Autors principals: Surma, Michelle, Handy, Caitlin, Chang, Jiang, Kapur, Reuben, Wei, Lei, Shi, Jianjian
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942480/
https://ncbi.nlm.nih.gov/pubmed/24595357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090758
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