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Dissecting the roles of ROCK isoforms in stress-induced cell detachment

The homologous Rho kinases, ROCK1 and ROCK2, are involved in stress fiber assembly and cell adhesion and are assumed to be functionally redundant. Using mouse embryonic fibroblasts (MEFs) derived from ROCK1(−/−) and ROCK2(−/−) mice, we have recently reported that they play different roles in regulat...

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Autors principals: Shi, Jianjian, Surma, Michelle, Zhang, Lumin, Wei, Lei
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680529/
https://ncbi.nlm.nih.gov/pubmed/23598717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24699
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