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Dissecting the roles of ROCK isoforms in stress-induced cell detachment

The homologous Rho kinases, ROCK1 and ROCK2, are involved in stress fiber assembly and cell adhesion and are assumed to be functionally redundant. Using mouse embryonic fibroblasts (MEFs) derived from ROCK1(−/−) and ROCK2(−/−) mice, we have recently reported that they play different roles in regulat...

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Detalhes bibliográficos
Main Authors: Shi, Jianjian, Surma, Michelle, Zhang, Lumin, Wei, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680529/
https://ncbi.nlm.nih.gov/pubmed/23598717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24699
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