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Disruption of ROCK1 gene restores autophagic flux and mitigates doxorubicin-induced cardiotoxicity
Doxorubicin is among the essential medicines with a wide antitumor spectrum, but its clinical application is limited by its cardiotoxicity. We recently discovered that ROCK1 is a key molecule in mediating cardiac remodeling in response to various stresses. To determine the roles of ROCK1 in doxorubi...
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| Publicado en: | Oncotarget |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Impact Journals LLC
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5849190/ https://ncbi.nlm.nih.gov/pubmed/29560126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24457 |
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