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Integrating folding kinetics and protein function: Biphasic kinetics and dual binding specificity in a WW domain

Because of the association of β-sheet formation with the initiation and propagation of amyloid diseases, model systems have been sought to further our understanding of this process. WW domains have been proposed as one such model system. Whereas the folding of the WW domains from human Yes-associate...

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Bibliografske podrobnosti
Main Authors: Karanicolas, John, Brooks, Charles L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC373479/
https://ncbi.nlm.nih.gov/pubmed/14981252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0304825101
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