Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte–neuron co-cultures

Hyperammonemia is a major etiological toxic factor in the development of hepatic encephalopathy. Brain ammonia detoxification occurs primarily in astrocytes by glutamine synthetase (GS), and it has been proposed that elevated glutamine levels during hyperammonemia lead to astrocyte swelling and cere...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Dadsetan, Sherry, Kukolj, Eva, Bak, Lasse K, Sørensen, Michael, Ott, Peter, Vilstrup, Hendrik, Schousboe, Arne, Keiding, Susanne, Waagepetersen, Helle S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2013
Onderwerpen:
Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734774/
https://ncbi.nlm.nih.gov/pubmed/23673435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.73
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items