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Codelivery of VEGF siRNA and Gemcitabine Monophosphate in a Single Nanoparticle Formulation for Effective Treatment of NSCLC

There is an urgent need for new therapeutics for the treatment of aggressive and metastatic refractory human non-small–cell lung cancer (NSCLC). Antiangiogenesis therapy and chemotherapy are the two major treatment options. Unfortunately, both types of therapies when used individually have their dis...

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Autori principali: Zhang, Yuan, Schwerbrock, Nicole MJ, Rogers, Arlin B, Kim, William Y, Huang, Leaf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734668/
https://ncbi.nlm.nih.gov/pubmed/23774791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.120
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