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Length-dependent structure formation in Friedreich ataxia (GAA)(n)·(TTC)(n) repeats at neutral pH
More than 15 human genetic diseases have been associated with the expansion of trinucleotide DNA repeats, which may involve the formation of non-duplex DNA structures. The slipped-strand nucleation of duplex DNA within GC-rich trinucleotide repeats may result in the changes of repeat length; however...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC373408/ https://ncbi.nlm.nih.gov/pubmed/14978261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh274 |
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