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Inhibitors of protein synthesis identified by a high throughput multiplexed translation screen

The use of small molecule inhibitors of cellular processes is a powerful approach to understanding gene function that complements the genetic approach. We have designed a high throughput screen to identify new inhibitors of eukaryotic protein synthesis. We used a bicistronic mRNA reporter to multipl...

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Autori principali: Novac, Olivia, Guenier, Anne-Sophie, Pelletier, Jerry
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC373382/
https://ncbi.nlm.nih.gov/pubmed/14769948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh235
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