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Reconstitution of the Vital Functions of Munc18 and Munc13 in Neurotransmitter Release
Neurotransmitter release depends critically on Munc18-1, Munc13, the Ca(2+) sensor synaptotagmin-1 and the SNAREs syntaxin-1, synaptobrevin and SNAP-25. In-vitro reconstitutions have shown that syntaxin-1-SNAP-25-liposomes fuse efficiently with synaptobrevin-liposomes in the presence of synaptotagmi...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733786/ https://ncbi.nlm.nih.gov/pubmed/23258414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1230473 |
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