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Transcription regulation of TNF-α-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cells

Poly(ADP-ribose) polymerase-1 (PARP-1) has been involved in endothelial cell dysfunction associated with various pathophysiological conditions. The intrinsic mechanism of PARP-1-mediated endothelial cell dysfunction could be related to PARP-1 overactivation, NAD(+) consumption and ATP depletion. An...

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Autors principals: Carrillo, Ana, Monreal, Yolanda, Ramírez, Pablo, Marin, Luis, Parrilla, Pascual, Oliver, Francisco Javier, Yélamos, José
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC373356/
https://ncbi.nlm.nih.gov/pubmed/14762203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh239
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