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Poly(ADP-ribose) polymerase (PARP-1) and p53 independently function in regulating double-strand break repair in primate cells

PARP-1 is rapidly activated by DNA strand breaks, which finally leads to the modulation of multiple protein activities in DNA replication, DNA repair and checkpoint control. PARP-1 may be involved in homologous recombination, and poly(ADP-ribosyl)ation of p53 represents one possible mechanism that a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Süsse, Silke, Scholz, Claus-Jürgen, Bürkle, Alexander, Wiesmüller, Lisa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC373350/
https://ncbi.nlm.nih.gov/pubmed/14757832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh227
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