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B Cells Are Required for Optimal CD4(+) and CD8(+) T Cell Tumor Immunity: Therapeutic B Cell Depletion Enhances B16 Melanoma Growth in Mice()

B lymphocytes can both positively and negatively regulate cellular immune responses. Previous studies have demonstrated augmented T cell-mediated tumor immunity in genetically B cell-deficient mice, suggesting that therapeutic B cell depletion would enhance tumor immunity. To test this hypothesis an...

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Detalhes bibliográficos
Main Authors: DiLillo, David J., Yanaba, Koichi, Tedder, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733120/
https://ncbi.nlm.nih.gov/pubmed/20194720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903009
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