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Cellular and molecular requirements for rejection of B16 melanoma in the setting of regulatory T cell depletion and homeostatic proliferation

We have recently demonstrated that adoptive transfer of regulatory T cell (Treg) - depleted polyclonal T cells into lymphopenic mice leads to rejection of B16 melanoma, which generated an opportunity to study host requirements for tumor rejection when it effectively occurred. CD8(+) T cell priming a...

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Autors principals: Kline, Justin, Zhang, Long, Battaglia, Lauren, Cohen, Kenneth S., Gajewski, Thomas F.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3294164/
https://ncbi.nlm.nih.gov/pubmed/22312128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100845
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